Overview
Melanotan II (MT-II) is a synthetic cyclic analogue of the α-MSH hormone.
Mechanism of action
A non-selective agonist of the melanocortin receptors (MC1R, MC3R, MC4R, MC5R). It stimulates eumelanin production (melanogenesis) independently of UV exposure. Its lack of selectivity is accompanied in the literature by a broad side-effect profile (e.g. nausea, flushing).
Research context
In preclinical research, MT-II has been studied beyond pigmentation: nerve regeneration and neuroprotection (sciatic nerve injury models in rats) and MC4R signalling related to food intake. Unapproved molecule.
Quality assurance
- Purity ≥ 99 % verified by HPLC
- Certificate of Analysis (COA) available per batch
- Traceability: unique batch number on every vial
Format & handling
Presentation: lyophilised powder, 10 mg / vial · Reconstitution: bacteriostatic water · Storage: refrigerate the lyophilisate; after reconstitution, keep cold and protected from light.
References
- « The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration… » (preclinical study).
For research use only. Product intended exclusively for scientific and laboratory research. Not intended for human or animal consumption.
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